google-site-verification=iUxCUgpoCQNGCS2CQuHi1L8aGqyfkykwcZUHtbSwrts The vitamin B3 analogue nicotinamide riboside has only very minor effects on reducing muscle damage in mdx mice
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The vitamin B3 analogue nicotinamide riboside has only very minor effects on reducing muscle damage in mdx mice

Preprint

February 6, 2023

Stan, Tiberiu Loredan

Summary

Our data showed a trend for increase in NAD+-levels in blood; only in the D2-mdx NR-treated mice the NAD+-levels were slightly increased. These markers were elevated in mdx models compared to controls, but not affected by the NR treatment. Histological analysis of muscle tissues indicated a mild treatment effect in D2-mdx mice. Based on our results, testing NR treatment in clinical trials in DMD patients is not warranted.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393969/

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Original work © 2022 by Right of Assembly

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IMPORTANT DISCLOSURES

1. Health Supplements Are Not Medicines. Health Supplements that raise NAD levels, like nicotinamide riboside or other NAD precursors, are not intended to diagnose, treat, cure, or prevent any disease.

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2. No Medical Advice. I am a lawyer and a journalist, not a doctor, and I offer no medical advice. But I do follow the science, and I can bring to your attention some interesting studies. You can read more about me here. And check with your physician -- your physician can look at this research, too.

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