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Nicotinamide riboside improves MI-induced acute kidney injury through increasing nicotinamide phosphorybosil transferase and NAD renal levels

Journal of Molecular and Cellular Cardiology

December 31, 2022

Habeichi, Nada


Strong evidence has demonstrated a link between acute myocardial infarction (MI) and acute kidney injury (AKI). A decrease in cardiac and renal nicotinamide adenine dinucleotide (NAD) has been reported post-cardiac and kidney diseases. The correlation between myocardial and kidney NAD homeostasis in the context of MI-induced AKI (Type-1 CRS) and the potential beneficial impact of NAD boosting therapies in this relatively unexplored disease model are yet to be determined.

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