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Nicotinamide mononucleotide ameliorates senescence in alveolar epithelial cells

MedComm

May 27, 2021

Fang, Tingting

Summary

There are many factors leading to cell senescence, including oxidative stress, mitochondrial dysfunction, and so on...NMN supplementation not only decreases the level of oxidative stress in cells, but also reduces the damage of cellular function induced by oxidative stress, including genetic instability, improves mitochondrial functions, and increases the activity of NAD+-dependent enzymes (e.g., SIRT family).

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