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Nicotinamide enhances myelin production after demyelination through reduction of astrogliosis and microgliosis

Frontiers in Cellular Neuroscience

August 17, 2023

Kaplanis, Stefanos loannis


Overall, we show that the increased myelin production that follows NAM treatment in vivo is accompanied by a decrease in both astrocyte and microglia accumulation at the lesion site. Our data indicate that NAM influences astrocytes and microglia directly, in favor of the remyelination process by promoting a less inflammatory environment.

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