Acute, short-term inflammation is essential to the body's healing process. Chronic, long-term inflammation can damage your body and lead to auto-immune diseases, as well as just about every other bad thing, like diseases of the kidney, liver, heart, brain, and cancer. It can cause anxiety and depression.

One study concluded that chronic inflammation was a "highly significant risk factor for both morbidity and mortality in the elderly people, as most if not all age-related diseases share an inflammatory pathogenesis." Persistent low-level chronic inflammation is really dangerous. It is a hallmark of aging. And you might not even know that you have it.

Some human clinical studies show that replenishing NAD levels reduces chronic inflammation. If that's correct, then for people worried about healthy aging, that would by itself be ample reason to use an NAD booster.